Sterilization of health care products — Radiation sterilization — Substantiation of 25 kGy as a sterilization dose
ISO 11137-2 was prepared by Technical Committee ISO/TC 198, Sterilization of health care products.
ABSTRACT
Gamma irradiation is today an accepted method of sterilization for petridishes, test tubes, syringes, dressing and other medical devices that can not easily be made germ free in other ways. The possibility of sterilizing culture media for the growth of microorganisms by gamma radiation were investigated by Becking (2) , Altmann et al. (1) , Bogokowsky and Altmann (3) , and Li et al. (4) It was reported by Altmann et al. (1) and Bogokowsky and Altmann (3) that gamma radiation offers an attractive and economical way of sterilizing media in sealed plastic containers, eliminating the need to sterilize media and container separately and avoiding the risk of contamination during processing. Such media may be kept for long periods in the laboratory and are always ready for use. Yang and Xiao (5) and Li et al. (4) found that using Co-60 gamma ray to sterilize the cultural materials of edible fungus is a secure and saving labor and energy new method which could sterilize thoroughly.
REFERENCES
(1) G.Altmann, E. Eisenberg and B. Bogokowsky ; Int. J. Appl. Rad. Isotopes; 30,527(1979).
(2) J.H.Becking; Misc. Papers 9, Landbouwhogeschool Wageningen; 9, 55(1971).
(3) B.Bogokowsky and G. Altmann; Int. J. Appl. Rad. Isotopes; 32, 891(1981).
(4) G.Li,Z.Guan and H. Zhao; Rad. Phys. Chem.; 42(4-6), 645(1993). (5) F.Yang and Z. Xiao; China. Food. Press.; 115(1988).
